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KMID : 0376219850220030557
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Chonnam Medical Journal
1985 Volume.22 No. 3 p.557 ~ p.571
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Sick Role Behavior of Patients Undergoing Chemotherapy for Cancer
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Abstract
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Fine structure of the processes of initial osteogenesis and cartilage resorption in metacarpal diathesis of human fetuses was studied by electron microscopy.
The cells of the inner osteoblastic and outer fibroblastic layers of the periosteum were arranged concentrically about the osteoid with their longitudinal axis aligned parallel to it. Osteoblast contained abundant rough endoplasmic reticulum and the Golgi apparatus. Small vesicles were associated with the Golgi apparatus as well as the extensive rough endoplasmic reticulum. The osteoblasts of the periosteum started to lay down a thin cylindrical sleeve of osteoid on the outer surface of the cartilage modes.
Most hypertrophied chondrocytes in the center of diathesis appeared to be disintegrating. From the periosteum of diathesis, vascular sprouts expanded within a recently opened lacunae, and the invading osteoblasts laid down osteoid and bone. Resorption of calcified matrix was undertaken by perivascular and multinucleated chondroclast. The resorption of calcified cartilage was restricted to the region of the ruffled border of the chondroclast.
The processes of initial osteogenesis in diathesis of metacarpal bone were found to possess morphological similarities to that occurring at the metaphysic side of the epiphyses plate.
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